Annnd A Special Thanks To Bryaco, Wow. This is the first time i've seen A Community-Staff Effort to fix a huge problem good job guys (y)
So I decided to check on this thread to see if there were any updates given that the game had decided to crash on me again a couple times tonight and to my stunned surprise, I see that there was, indeed, a fix out there! Thank you so much!
May 2016 - last edited May 2016
@Flubbervdv In steam > right click on Mass Effect > Properties > click the "Local Files" Tab > Verify integrity of Game cache.
Make also sure that "Always keep this game up to date" is set under the "Update" tab.