Sorry to hear about this.
Have you tried the following steps?
1. Turn off the Origin in-game Overlay in the Origin Launcher
2. Clear Origin Cache: https://help.ea.com/en-us/help/faq/clear-cache-to-fix-problems-with-your-games/
3. Uninstall/Reinstall Origin: https://help.ea.com/en-us/help/origin/origin/manually-uninstalling-origin/
4. Clean Boot: https://help.ea.com/en/help/faq/how-to-clean-boot-your-pc/
Try these steps, and let us know if you still encounter this issue.
i done it all, however, in general,it didn't help as much, i have stop doing that, only tried repair option, and look forward the game be fixed / updated
Sorry to hear those steps didn't work out for you.
I play on PC as well, and haven't encountered any Crashing issues lately.
Have you also tried creating a new Windows User Account, and launching Anthem under that Account to see if it still crashes?