@Kociak86 it looks like a Mod issue. Remove all of your mods and custom content, delete the localthumbcache.package file. Reopen your game and try a new save. If the issue does not appear then it is a mod issue.
You'll need to test which Mod/CC it is: 1) make sure you have the latest versions of each Mod/CC you want to download. There was a patch recently which means that Mods/CCs often need to be updated.
2) use the 50-50 method to identify which Mod/CC is causing the issue.