That is the "FPSCounter" mode from Nexus?
You downloaded the Standalone installer from the Nexus page directly?
What is exactly happening?
Try to repair the game. (in Origin > Game Library > right click ME1 > Repair)
Test if the game works > If yes, download the installer again > Install the mode > Test.
If it still won't work:
Create a DxDiag in text file format and post it with your next reply.
If you use Windows 7 also go to your Reliability monitor > Press the Windows key and "R" at the same time and copy and paste or type "perfmon /rel" (without the quotes) in the new Window > hit “ENTER” and look if it has entries for the game you have trouble with.
If yes double click at the last entry for the game executable, copy the info to the clipboard, and save it to a text file.
You can attach the DxDiag text file you created (and the “Reliability monitor” text file as well) to your post in the “Reply” window with the “Choose File” button.