Mass Effect 1 won't launch

[07_AlPacino_YT]

I have the same problem and looks like its becauze I have i5-7600k and I run windows 8 and beacauze Microsoft doesnt give any update support for last generation of processors that run Win 8 and 7 exept 10,so we need to install win 10 so that game can work again...Microsoft and theyr marketing -.-

[ThandalNLyman]

I've had ME1 since, well... ever.  It ran (and runs) fine on Win7, Win8, Win8.1, and Win10.  I've played it with all of them.

Bottom Line:  It's not the OS that's the problem!

Some more technical information (like a DXDiag dump as described in the pinned topic) would help.