November 2014
Win7 64bit.
Mass efect 1 just downloaded and installed from Origin without any problems.
When I start the game, the process is starting (I can see it in task manager), then it's closing by itself.
November 2014
If you haven't already, read the following thread: http://answers.ea.com/t5/Mass-Effect-1/PC-Mass-Effect-Won-t-Start-A-New-Solution/td-p/1435666
November 2014
I had the same trouble.
I eventually figured something out.
Go to Local Disk > program files> Origin games> Mass effect > Binaries
you will then see the chrome M, right click on that and choose properties, then compatibility and check the button that says " run this program in compatibility mode for" then choose Windows Xp service pack 3 then click the button that says run in administration mode.
Hopefully it works for you