I have been looking for the solution since 2018 September. I can't do anything about it, it happens even if -There are 30 GB on my C: drive
-I copied the things from game0.old to game0
- I regenerated the entire SPORE folder
-Running Spore with Admin rights
My specs: Intel I3 540, 4GB RAM. OS: Windows 8.1
If you do all those steps, please contact a game advisor for further assistance!