July 2016
Sorry for the late reply.
Due to some personal stuff that's been happening lately I haven't had much time to play or to test.
However I have some VERY good news.
It seems that the crashing has stopped, after the last troubleshooting tests I have played about 13 more hours without a single crash.
At the end these 3 steps are probably what solved it:
1. Use my Onboard sound instead of my dedicated soundcard.
2. Disable Raptr
3. Disable my MSI Afterburner overclocking.
I completely forget about the last 2 steps.
I don't like Raptr at all, it causes issues for more games lately like crashing on startup for example, I only use it to "farm" points, disabled everything else in that program but I know it's bloatware and you may hate me for it :P
I also forgot about MSI afterburner, it never gave me problems but when I disabled it, it got rid of more crashing, I don't use the overlay of any of these programs but Mass Effect didn't like these.
Thanks for all the help you have given me to resolve this issue, in all honesty you were a lot more helpful then the "specialists" from EA, you should get paid by them instead :P
July 2016
Hi @Selvator
Good to hear that it works, and Thanks for the XP.
I think that the renaming of the DLL also played a roll, but be that as it may the important thing is that it works now.
January 2017
March 2017
I know this may be late, but turning off hardware acceleration for sound did it for me... so far. (I already had SP3 compatibility, and have up to date drivers otherwise.) I'm on about 1.5 hours without a crash, but I was getting a crash every 20 min or so, since I hadn't gotten off the Citidel.
March 2017
Okay, so I'm still getting crashes, but it's taking generally 2-3+ hours. I typically don't play this long, today being the first day of spring break. The only other thing I could think of is MSI Afterburner... if I notice no crashes until next weekend, I'll post back. But turning off hardware acceleration for sound GREATLY helped.
March 2017
MSI afterburner is something you could definitely try it worked for me along with changing my sound driver.
March 2017
Yeah, I put 52ish hours into (most of) the full game. Never got one more crash after disabling MSI.
But if you still want MSI, I found I'd get the convo crashes about once every 1-2 hours when hardware acceleration for sound was off.
May 2018
Problem definitely seems to be MSI Afterburner. I for the life of me couldn't figure out why I kept getting crashes when talking to people on the Normandy. Followed your advice on disabling afterburner and no more crashes (so far). Anyways thank you.
September 2018
After turning off hardware acceleration for sound a week ago there were no more crashes (7 h of gaming). The OS is Win10 Pro v1803; Overclocking didn't play a role since there was no overclocking.