October 2017
http://answers.ea.com/t5/Dead-Space-Games/unable-to-start-game/td-p/5917521/page/3
This SOLUTION worked for me, as well as the author of the original post.
The issue, specifically in my scenario, is the Dead Space 2 folder in the User/Documents folder, where saved games are located for EA Games.
I have all three versions of Dead Space. It wasn't until I removed the Dead Space 2 folder from the EA Folder in the User Documents folder, that the crash stopped occurring.
Now instead of Dead Space 2 and Dead Space 3 folders, I have only Dead Space 3.
December 2017
I just purchased the first Dead space and was having this issue, "run as administrator" worked like a champ! Thank You for your knowledgeable assistance. It is running through GeForce Experience without a single hiccup. Thanks Again!
January 2019
April 2021